News Here you can find current info, event notes and other news.

Here you can find current info, event notes and other news.

New publication on the optimization of hollow fiber membranes

In the article entitled "Optimizing the Axial Resistance Profile of Submerged Hollow Fiber Membranes," the method of optimal control is used to predict the resistance profile of  hollow fiber membranes which guarantees a constant transmembrane flux.

Heiko Briesen is honored with Bavarian Prize for Excellence in Teaching.

We are happy and thankful for the recognition of our efforts in high quality teaching.

New Publication: Capturing Crystal Shape Evolution from Molecular Simulations

A simple and efficient algorithm for tracking shape evolution of small-molecule organic crystals during molecular simulations is described. No information except the unit cell parameters is needed beforehand, making it feasible to automatically detect not only existing but also new forming crystal faces and edges, which is valuable for prediction of growth and dissolution kinetics. Paper

Our colleague Mathias Hilmer was awarded with the price for outstanding scientific work.

We congratulate our colleague Mathias Hilmer, who has been awarded the prize of the “Weihenstephaner Milchwirtschaftler, Bio- und Lebensmitteltechnologen e.V.”  for outstanding scientific work for his master's thesis entitled: "Development of a freeze-drying stage for µ-CT measurements". The prize was awarded during the association's digital autumn conference on October 15, 2020.


New Publication: A novel method for assessing the coating uniformity of hot-melt coated particles using micro-computed tomography

This study presents a new method for identifying and quantifying factors influencing coating uniformity of hot-melt coated particles. The proposed method facilitates the determination of coating-thickness distribution and non-covered surface proportion based on micro-computed tomography measurements.

Award for the best digital teaching

We are pleased to receive this year's award for the best digital teaching from the student council for brewing, food technology and bioprocess engineering. The award ceremony took place on a small scale at the chair.

Keynote lecture of Heiko Briesen on crystal shape characterization on Youtube

On September, 10th, 2020, Heiko Briesen gave an online keynote lecture with the title “Crystallization processes in four dimensions – Tracking full crystal shape information over time”in the webinar Series 2020 of the Working Party on Crystallization EFCE

New Publication: Morphological and physiological characterization of filamentous Lentzea aerocolonigenes: Comparison of biopellets by microscopy and flow cytometry

Morphological and physiological characterization of filamentous Lentzea aerocolonigenes: Comparison of biopellets by microscopy and flow cytometry

New Publication: Development of a Freeze-Drying Stage for In-Situ µ-CT Measurements

This article shows a new conceptional design of an experimental setup for in situ visualization of the lyophilization process using neutron radiography and computed tomography and its validation. The setup is designed for the neutron imaging beam line ANTARES at FRM II, considering all the requirements for this method. Neutrons are ideally suited to detect water in a sample because of the high neutron attenuation of hydrogen, whereas other materials like aluminum have a low absorption of neutrons resulting in an image where the drying fronts in bulk materials are observable. Consisting of a freeze-drying cell and a sample-stick, the setup is basically inspired by a common freeze-drying unit. The cell is axial symmetrical to allow computed tomography measurements. The developed sample stick connects the vacuum cell with the measurement devices and the vacuum pump. Experiments were performed at FRM II, showing that the setup is functional. In addition, the experiments discovered some possibilities for improvements, which can be used in further measurements.  Paper

New research article published on the swelling of roasted coffee particles

In this study, the swelling behavior of roasted coffee particles in water and particularly its impact on particle diameter is examined by applying laser?diffraction analysis and microscopy. Several potential influencing factors are investigated: initial particle size, roasting degree, and temperature. Additionally, the time dependency of swelling and particle shape is evaluated at two different temperatures.


New Papaer: Characterization of Lyophilization of Frozen Bulky Solids.

Two methods to study the primary freeze?drying behavior of bulky solids are presented, namely, lyomicroscopy and neutron imaging. The applicability of both methods to visualize the evolution of the sublimation front is tested for maltodextrin particles with different sizes and solid concentrations. Exemplary results for both methods are reported and the applicability of both methods to study freeze?drying behavior of bulk solids is described. To estimate the impact of particle size and bed height for the freeze?drying of bulky solids, a modified Biot number is introduced to estimate the optimum particle size for a given bed height and formulation. The applicability of the two methods with regard to the modified Biot numbers is discussed. Link

What happens actually during freeze-drying?

Researchers of the chair of process systems engineering, in cooperation with the Otto von Guericke University, investigate the freeze-drying process by using neutrons. Link

Novel parameter estimation method for cake filtration published

Parameter Estimation for Incompressible Cake Filtration: Advantages of a Modified Fitting Method

What is the influence of particle shape?

Using 3D printed particles to investigate fundamental particle and packing properties. Particle shape matters – Using 3D printed particles to investigate fundamental particle and packing properties

Novel multiscale approach for optimizing depth filters published

Designing optimally-graded depth filter media using a novel multiscale method

From three-dimensional morphology to effective diffusivity in filamentous fungal pellets

From three-dimensional morphology to effective diffusivity in filamentous fungal pellets.
Joint publication with TU Berlin.
Title: From three-dimensional morphology to effective diffusivity in filamentous fungal pellets

What does "process system engineering" mean? - Suggested answer in new article.

System Process Engineering - A Philosophical Concept Analysis

Open access full text available at

New publication on impedance spectroscopy

Impedance spectroscopy as a process analytical technology (PAT) tool for online monitoring of sucrose crystallization.

New publication on triboelectric separation

Effect of particle-wall interaction on triboelectric separation of fine particles in a turbulent flow

Joint publication with TU Berlin about 3D image analysis of filamentous fungi used in bioprocesses

Cooperation Partner:

  • TU Berlin, Institute of Biotechnology, Department of Applied and Molecular Microbiology
  • TU Munich, Chair of Technical Microbiology

Title: An X-ray microtomography-based method for detailed analysis of the three-dimensional morphology of fungal pellets

New publication on predicting self-diffusion coefficient

Analysis of two common algorithms to compute self-diffusion coefficients in infinite dilution from molecular dynamics simulations and application to n-alkanes (C1 to C35) in water in Fluid Phase Equilibria

Our colleague Moritz Kindlein was awarded third place for the best presentation of the ProcessNet Subject Division Food Technology.

We congratulate our colleague Moritz Kindlein, who was honored at this year's annual meeting of the ProcessNet Subject  Division Food Technology. The annual meeting took place at the Nestle Research Center in Lausanne. He achieved third place with the presentation "Modeling the refining of chocolate and related molecular mechanisms with impact on rheology".

Joint work with the Institute of Biochemical Engineering (TUM) published

"Enhancing the X-ray contrast of polymeric biochromatography particles for three-dimensional imaging"
Journal of Chromatography A

New Season's Greetings

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New open access publication on flotation in cooperation with BASF

Modeling the Separation of Microorganisms in Bioprocesses by Flotation

Interdisciplinary open-access publication on "opinion dynamics"

Population Balance Modeling and Opinion Dynamics - A Mutually Beneficial Liaison?
(DOI: 10.3390/pr6090164)

New publications on filtration

"Decreasing Filter Cake Resistance Using Packing Structures"
 (DOI: 10.1002/ceat.201800254)

"Increasing Wort Flow by Flocculation of Fine Particle Fractions"

 (DOI: 10.23763/BrSc18-09bandelt)

Oral presentations:
Stefan Schmideder, Christoph Kirse, Julia Hofinger, Sascha Rollié, and Heiko Briesen: "Modeling the separation of microorganisms in bioprocesses by flotation"

Michael Kuhn, Christoph Kirse, and Heiko Briesen: "Population balance modeling and opinion dynamics –a mutually beneficial liaison?"

Christoph Kirse and Heiko Briesen: "Fixed pivot technique for solving a  bivariate model of enzymatic depolymerization of branched starch"

Tijana Kovacevic and Heiko Briesen: "A new, area - preserving model of crystal growth and aggregation"

Stefan Schmideder, Tiaan Friedrich, Tijana Kovacevic, Lars Barthel, Philipp Kunz, Vera Meyer, Rudibert King and Heiko Briesen: "Growth of filamentous microorganisms: PBM and experimental determination of rate equations"